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1

Crystal Structure of a Ternary FGF-FGFR-Heparin Complex Reveals a Dual Role for Heparin in FGFR Binding and Dimerization

Joseph Schlessinger, Alexander N. Plotnikov, Omar A. Ibrahimi, Anna V. Eliseenkova, Brian K. Yeh, Avner Yayon, Robert J. Linhardt, Moosa Mohammadi

Journal:

Year:

2000

Language:

english

File:

PDF, 406 KB

english, 2000

2

Susceptibility of Human Malaria Parasites to Chloroquine is pH Dependent

Avner Yayon, Z. Ioav Cabantchik and Hagai Ginsburg

Journal:

Proceedings of the National Academy of Sciences

Year:

1985

Language:

english

File:

PDF, 882 KB

english, 1985

3

Production of Bioactive, Post-Translationally Modified, Heterotrimeric, Human Recombinant Type-I Collagen in Transgenic Tobacco †

Stein, Hanan, Wilensky, Michal, Tsafrir, Yehuda, Rosenthal, Michal, Amir, Rachel, Avraham, Tal, Ofir, Keren, Dgany, Or, Yayon, Avner, Shoseyov, Oded

Journal:

Biomacromolecules

Year:

2009

Language:

english

File:

PDF, 1.04 MB

english, 2009

4

Fibrin-hyaluronic acid hydrogel-based delivery of antisense oligonucleotides for ADAMTS5 inhibition in co-delivered and resident joint cells in osteoarthritis

Garcia, João Pedro, Stein, Jeroen, Cai, Yunpeng, Riemers, Frank, Wexselblatt, Ezequiel, Wengel, Jesper, Tryfonidou, Marianna, Yayon, Avner, Howard, Kenneth A., Creemers, Laura B.

Journal:

Journal of Controlled Release

Year:

2019

Language:

english

File:

PDF, 3.21 MB

english, 2019

5

Hydrogel-based delivery of antimiR-221 enhances cartilage regeneration by endogenous cells

Lolli, Andrea, Sivasubramaniyan, Kavitha, Vainieri, Maria L., Oieni, Jacopo, Kops, Nicole, Yayon, Avner, van Osch, Gerjo J.V.M.

Journal:

Journal of Controlled Release

Year:

2019

Language:

english

File:

PDF, 2.05 MB

english, 2019

6

Staurosporine induces neurite outgrowth in neuronal hybrids (PC12EN) lacking NGF receptors

David Rasouly, Davidit Shavit, Ramiro Zuniga, Rafael B. Elejalde, Brian R. Unsworth, Avner Yayon, Philip Lazarovici, Peter I. Lelkes

Journal:

Journal of Cellular Biochemistry

Year:

1996

Language:

english

File:

PDF, 1.77 MB

english, 1996

7

Soluble and matrix-associated heparan sulfate proteoglycans increase expression of erb-B2 and erb-B3 in colon cancer cell lines

Isabel Zvibel, Shlomo Brill, Zamir Halpern, Sharon Moskovitz, Avner Yayon, Moshe Papa

Journal:

International Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 153 KB

english, 2001

8

Differential expression of the two VEGF receptors flt and KDR in placenta and vascular endothelial cells

Bernhard Barleon, Stefanie Hauser, Claudia Schöllmann, Karin Weindel, Dieter Marmé, Avner Yayon, Herbert A. Weich

Journal:

Journal of Cellular Biochemistry

Year:

1994

Language:

english

File:

PDF, 996 KB

english, 1994

9

Heparan sulfate primed on β-D-xylosides restores binding of basic fibroblast growth factor

Hua-Quan Miao, Timothy A. Fritz, Jeffrey D. Esko, Joseph Zimmermann, Avner Yayon, Dr. Israel Vlodavsky

Journal:

Journal of Cellular Biochemistry

Year:

1995

Language:

english

File:

PDF, 1.12 MB

english, 1995

10

Identification of a neutralizing antibody determinant on basic fibroblast growth factor by screening a random phage-epitope library

Avner Yayon, David Aviezer, Michal Safran, Janet L. Gross, Yehudit Heldman, Shmuel Cabilly, David Givol, Ephraim Katchalski-Katzir

Journal:

Journal of Molecular Recognition

Year:

1995

Language:

english

File:

PDF, 153 KB

english, 1995

11

Interaction between basic fibroblast growth factor and the anti-angiogenic drug PNU145156E

Moreno Zamai, Chithra Hariharan, Dina Pines, Michal Safran, Avner Yayon, Valeria R. Caiolfa, Mariangela Mariani, Ehud Pines, Rivka Cohen-Luria, Abraham H. Parola

Journal:

Journal of Molecular Structure

Year:

2006

Language:

english

File:

PDF, 583 KB

english, 2006

12

Electrical impedance scanning: a new approach to skin cancer diagnosis

Yaël A. Glickman, Orna Filo, Magda David, Avner Yayon, Moris Topaz, Bosmat Zamir, Alexander Ginzburg, Dganit Rozenman, Gad Kenan

Journal:

Skin Research and Technology

Year:

2003

Language:

english

File:

PDF, 468 KB

english, 2003

13

Basic fibroblast growth factor: a potential inhibitor of glutamine synthetase expression in injured neural tissue

Yelena Kruchkova, Iris Ben-Dror, Avia Herschkovitz, Magda David, Avner Yayon, Lily Vardimon

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 501 KB

english, 2001

14

Heparin-like inhibitory activity to fibroblast growth factor-2 in wound fluids of patients with chronic skin ulcers and its modulation during wound healing

Zvi Landau, Magda David, David Aviezer, Avner Yayon

Journal:

Wound Repair and Regeneration

Year:

2001

Language:

english

File:

PDF, 124 KB

english, 2001

15

Autocrine regulation of cell growth and transformation by basic fibroblast growth factor

Avner Yayon, Michael Klagsbrun

Journal:

Cancer and Metastasis Reviews

Year:

1990

Language:

english

File:

PDF, 976 KB

english, 1990

16

Reconstitution of fibroblast growth factor receptor interactions in the yeast two hybrid system

Ronit Aloni-Grinstein, Andrew Seddon, Avner Yayon

Journal:

Molecular Biotechnology

Year:

1999

Language:

english

File:

PDF, 1.26 MB

english, 1999

17

Effects of Chloroquine on the Feeding Mechanism of the Intraerythrocytic Human Malarial Parasite Plasmodium falciparum

AVNER YAYON, RINA TIMBERG, SHOSHANA FRIEDMAN, HAGAI GINSBURG

Journal:

Journal of Eukaryotic Microbiology

Year:

1984

Language:

english

File:

PDF, 2.60 MB

english, 1984

18

Stage-Dependent Effects of Chloroquine on Plasmodium falciparum In Vitro

AVNER YAYON, JOHN A. VANDE WAA, MALKA YAYON, TIMOTHY G. GEARY, JAMES B. JENSEN

Journal:

Journal of Eukaryotic Microbiology

Year:

1983

Language:

english

File:

PDF, 733 KB

english, 1983

19

Suppression of autocrine cell proliferation and tumorigenesis of human melanoma cells and fibroblast growth factor transformed fibroblasts by a kinase-deficient FGF receptor 1: evidence for the involvement of Src-family kinases

Yayon, Avner, Ma, Yong-Sheng, Safran, Michal, Klagsbrun, Michael, Halaban, Ruth

Journal:

Year:

1997

Language:

english

File:

PDF, 479 KB

english, 1997

20

Induction of Mdm2 and enhancement of cell survival by bFGF

Shaulian, Eitan, Resnitzky, Dalia, Shifman, Ohad, Blandino, Giovanni, Amsterdam, Abraham, Yayon, Avner, Oren, Moshe

Journal:

Year:

1997

Language:

english

File:

PDF, 460 KB

english, 1997

21

CD44 Involvement in Autoimmune Inflammations : The Lesson to be Learned from CD44-Targeting by Antibody or from Knockout Mice

DAVID NAOR, SHLOMO NEDVETZKI, MARITA WALMSLEY, AVNER YAYON, EVA A. TURLEY, IRA GOLAN, DAN CASPI, LORA ESHKAR SEBBAN, YEHIEL ZICK, TALI GARIN, DIMITRIOS KARUSSIS, NATHALIE ASSAYAG-ASHERIE, ITAMAR RAZ,

Journal:

Annals of the New York Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 95 KB

english, 2007

22

Skeletal Dysplasia and Defective Chondrocyte Differentiation by Targeted Overexpression of Fibroblast Growth Factor 9 in Transgenic Mice

Silvio Garofalo, Michal Kliger-Spatz, Jeremy L. Cooke, Orit Wolstin, Gregory P. Lunstrum, Sharon M. Moshkovitz, William A. Horton, Avner Yayon

Journal:

Journal of Bone and Mineral Research

Year:

1999

Language:

english

File:

PDF, 248 KB

english, 1999

23

Differential Activation of Cysteine-Substitution Mutants of Fibroblast Growth Factor Receptor 3 Is Determined by Cysteine Localization

Rivka Adar, Efrat Monsonego-Ornan, Pe'er David, Avner Yayon

Journal:

Journal of Bone and Mineral Research

Year:

2002

Language:

english

File:

PDF, 1.62 MB

english, 2002

24

Identifying the binding mode of a molecular scaffold

Doron Chema, Doron Eren, Avner Yayon, Amiram Goldblum, Andrea Zaliani

Journal:

Journal of Computer-Aided Molecular Design

Year:

2004

Language:

english

File:

PDF, 478 KB

english, 2004

25

Fibroblast Growth Factor 4 and Its Novel Splice Isoform Have Opposing Effects on the Maintenance of Human Embryonic Stem Cell Self-Renewal

Yoav Mayshar, Eran Rom, Irina Chumakov, Achia Kronman, Avner Yayon, Nissim Benvenisty

Journal:

Year:

2008

Language:

english

File:

PDF, 999 KB

english, 2008

26

Effect of diadenosine polyphosphates in achondroplasic chondrocytes: Inhibitory effect of Ap4A on FGF9 induced MAPK cascade

Ana Guzmán-Aránguez, Marta Irazu, Avner Yayon, Jesús Pintor

Journal:

Biochemical Pharmacology

Year:

2007

Language:

english

File:

PDF, 1.73 MB

english, 2007

27

Effect of PPADS on achondroplasic chondrocytes: Inhibition of FGF receptor type 3 over-activity

Ana Guzmán-Aránguez, Almudena Crooke, Avner Yayon, Jesús Pintor

Journal:

European Journal of Pharmacology

Year:

2008

Language:

english

File:

PDF, 391 KB

english, 2008

28

Detection and quantification of complexed and free soluble human vascular endothelial growth factor receptor-1 (sVEGFR-1) by ELISA

Carsten Hornig, Tanja Behn, Wolfgang Bartsch, Avner Yayon, Herbert A Weich

Journal:

Journal of Immunological Methods

Year:

1999

Language:

english

File:

PDF, 222 KB

english, 1999

29

Insight into Schmid Metaphyseal Chondrodysplasia from the Crystal Structure of the Collagen X NC1 Domain Trimer

Oren Bogin, Marc Kvansakul, Eran Rom, Josef Singer, Avner Yayon, Erhard Hohenester

Journal:

Year:

2002

Language:

english

File:

PDF, 419 KB

english, 2002

30

Heparin Differentially Regulates the Interaction of Fibroblast Growth Factor-4 with FGF Receptors 1 and 2

David Aviezer, Michal Safran, Avner Yayon

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 85 KB

english, 1999

31

Mapping a Heparin Binding Site on ErbB-3 Epidermal Growth Factor Receptor

Rivka Adar, Avner Yayon

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 195 KB

english, 2001

32

Developmental Localization of the Splicing Alternatives of Fibroblast Growth Factor Receptor-2 (FGFR2)

Avi Orr-Urtreger, Mark T. Bedford, Tatjana Burakova, Esther Arman, Yitzhak Zimmer, Avner Yayon, David Givol, Peter Lonai

Journal:

Developmental Biology

Year:

1993

File:

PDF, 1.93 MB

1993

33

Differential Binding Characteristics and Cellular Inhibition by Soluble VEGF Receptors 1 and 2

Wolfgang Roeckl, Dalit Hecht, Helena Sztajer, Johannes Waltenberger, Avner Yayon, Herbert A. Weich

Journal:

Experimental Cell Research

Year:

1998

Language:

english

File:

PDF, 312 KB

english, 1998

34

Mapping of Murine Fibroblast Growth Factor Receptors Refines Regions of Homology between Mouse and Human Chromosomes

Karen B. Avraham, David Givol, Aaron Avivi, Avner Yayon, Neal G. Copeland, Nancy A. Jenkins

Journal:

Year:

1994

File:

PDF, 151 KB

1994

35

The transport of chloroquine across human erythrocyte membranes is mediated by a simple symmetric carrier

Avner Yayon, Hagai Ginsburg

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1982

Language:

english

File:

PDF, 470 KB

english, 1982

36

A novel form of FGF receptor-3 using an alternative exon in the immunoglobulin domain III

Aaron Avivi, Avner Yayon, David Givol

Journal:

Year:

1993

Language:

english

File:

PDF, 425 KB

english, 1993

37

P2Y receptors activated by diadenosine polyphosphates reestablish Ca2+ transients in achondroplasic chondrocytes

Ana Guzmán-Aránguez, Marta Irazu, Avner Yayon, Jesús Pintor

Journal:

Year:

2008

Language:

english

File:

PDF, 987 KB

english, 2008

38

Transplanted blood-derived endothelial progenitor cells (EPC) enhance bridging of sheep tibia critical size defects

Nimrod Rozen, Tova Bick, Alon Bajayo, Ben Shamian, Michal Schrift-Tzadok, Yankel Gabet, Avner Yayon, Itai Bab, Michael Soudry, Dina Lewinson

Journal:

Year:

2009

Language:

english

File:

PDF, 1.74 MB

english, 2009

39

Assessment of cartilage repair after chondrocyte transplantation with a fibrin-hyaluronan matrix – Correlation of morphological MRI, biochemical T2 mapping and clinical outcome

Iris Eshed, Siegfried Trattnig, Michal Sharon, Ron Arbel, Gabriel Nierenberg, Eli Konen, Avner Yayon

Journal:

European Journal of Radiology

Year:

2012

Language:

english

File:

PDF, 1.02 MB

english, 2012

40

Crystal structure of the collagen α1(VIII) NC1 trimer

Marc Kvansakul, Oren Bogin, Erhard Hohenester, Avner Yayon

Journal:

Year:

2003

Language:

english

File:

PDF, 1.49 MB

english, 2003

41

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

Avner Yayon, Michael Klagsbrun, Jeffrey D. Esko, Philip Leder, David M. Ornitz

Journal:

Year:

1991

Language:

english

File:

PDF, 1011 KB

english, 1991

42

Nature of Interaction between Basic Fibroblast Growth Factor and the Antiangiogenic Drug 7,7-(Carbonyl-Bis[Imino-N-Methyl-4,2-Pyrrolecarbonylimino[N-Methyl-4,2-Pyrrole]-Carbonylimino])-Bis-(1,3-Naphtalene Disulfonate). II. Removal of Polar Interactions Affects Protein Folding

Zamai, Moreno, Hariharan, Chithra, Pines, Dina, Safran, Michal, Yayon, Avner, Caiolfa, Valeria R., Cohen-Luria, Rivka, Pines, Ehud, Parola, Abraham H.

Journal:

Biophysical Journal

Year:

2002

Language:

english

File:

PDF, 197 KB

english, 2002

43

Perlecan, basal lamina proteoglycan, promotes basic fibroblast growth factor-receptor binding, mitogenesis, and angiogenesis

David Aviezer, Dalit Hecht, Michal Safran, Magdalena Eisinger, Guido David, Avner Yayon

Journal:

Year:

1994

Language:

english

File:

PDF, 5.77 MB

english, 1994

44

Anti-VEGFR-2 scFvs for Cell Isolation. Single-Chain Antibodies Recognizing the Human Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2/flk-1) on the Surface of Primary Endothelial Cells and Preselected CD34+ Cells from Cord Blood

Thomas Böldicke, Michael Tesar, Carsten Griesel, Manfred Rohde, Hermann-Josef Gröne, Johannes Waltenberger, Orit Kollet, Tsvee Lapidot, Avner Yayon, Herbert Weich

Journal:

Year:

2001

Language:

english

File:

PDF, 336 KB

english, 2001

45

Matrix Metalloproteinase 2 Releases Active Soluble Ectodomain of Fibroblast Growth Factor Receptor 1

Ehud Levi, Rafael Fridman, Hua-Quan Miao, Yong-Sheng Ma, Avner Yayon and Israel Vlodavsky

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.15 MB

english, 1996

46

A Mouse Model for Achondroplasia Produced by Targeting Fibroblast Growth Factor Receptor 3

Yingcai Wang, Michal K. Spatz, Karuppiah Kannan, Hovhannisyan Hayk, Aaron Avivi, Marat Gorivodsky, Mark Pines, Avner Yayon, Peter Lonai and David Givol

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.97 MB

english, 1999

47

Opiates do not violate the viability and proliferative activity of human articular chondrocytes

Chechik, Ofir, Arbel, Ron, Salai, Moshe, Gigi, Roy, Beilin, Mark, Flaishon, Ron, Sever, Ronen, Khashan, Morsi, Ben-Tov, Tomer, Gal-Levy, Ronit, Yayon, Avner, Blumenstein, Sara

Journal:

Cell and Tissue Banking

Year:

2014

Language:

english

File:

PDF, 276 KB

english, 2014

48

Asparagine-344 Is a Key Residue for Ligand Binding in Keratinocyte Growth Factor Receptor †

Gray, Tamara E., Eisenstein, Miriam, Yayon, Avner, Givol, David

Journal:

Year:

1996

Language:

english

File:

PDF, 240 KB

english, 1996

49

Properly Oriented Heparin−Decasaccharide-Induced Dimers Are the Biologically Active Form of Basic Fibroblast Growth Factor †,‡

Moy, Franklin J., Safran, Michal, Seddon, Andrew P., Kitchen, Doug, Böhlen, Peter, Aviezer, David, Yayon, Avner, Powers, Robert

Journal:

Year:

1997

Language:

english

File:

PDF, 242 KB

english, 1997

50

Molecular Modeling Based Mutagenesis Defines Ligand Binding and Specificity Determining Regions of Fibroblast Growth Factor Receptors

Gray, Tamara E., Eisenstein, Miriam, Shimon, Tova, Givol, David, Yayon, Avner

Journal:

Year:

1995

Language:

english

File:

PDF, 3.28 MB

english, 1995

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